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The Number of Responding CD4 T Cells and the Dose of Antigen Conjointly Determine the Th1/Th2 Phenotype by Modulating B7/CD28 Interactions

โœ Scribed by Rudulier, C. D.; McKinstry, K. K.; Al-Yassin, G. A.; Kroeger, D. R.; Bretscher, P. A.


Book ID
124082732
Publisher
American Association of Immunologists
Year
2014
Tongue
English
Weight
1013 KB
Volume
192
Category
Article
ISSN
0022-1767

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More antigen-dependent CD4+ T cell / CD4
โœ Nahed Ismail; Peter A. Bretscher ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 110 KB ๐Ÿ‘ 2 views

Mechanisms controlling the Th1/Th2 phenotype of a primary immune response are often discussed assuming that the generation of Th1 and Th2 cells from the common CD4 + precursor T helper (pTh) involves an interaction of this pTh cell with an antigen-presenting cell (APC) in the form of a two-cell inte