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The Nucleotide Sequence of a 39 kb Segment of Yeast Chromosome IV: 12 New Open Reading Frames, Nine Known Genes and One Gene for Gly-tRNA

✍ Scribed by BAHR, ANDRÉ; MÖLLER-RIEKER, SABINE; HANKELN, THOMAS; KRAEMER, CHRISTIANE; PROTIN, URSULA; SCHMIDT, ERWIN R.

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
198 KB
Volume
13
Category
Article
ISSN
0749-503X

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✦ Synopsis

The complete nucleotide sequence of a 39 090 bp segment from the left arm of yeast chromosome IV was determined.

Twenty-one open reading frames (ORFs) longer than 100 amino acids and a Gly-tRNA gene were discovered. Nine of the 21 ORFs (D0892, D1022, D1037, D1045, D1057, D1204, D1209, D1214, D1219) correspond to the previously sequenced Saccharomyces cerevisiae genes for the NAD-dependent glutamate dehydrogenase (GDH), the secretory component (SHR3), the GABA transport protein (UGA4), the high mobility group-like protein (NHP2), the hydroxymethylbilane synthase (HEM3), the methylated DNA protein-cysteine S-methyltransferase (MGT1), a putative sugar transport protein, the Shm1 protein (SHM1) and the anti-silencing protein (ASF2). The inferred amino acid sequences of 11 ORFs show significant similarity with known proteins from various organisms, whereas the remaining ORF does not share any similarity with known proteins. The nucleotide sequence has been

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