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The Nuclear Pore Complex: The Gateway to Successful Nonviral Gene Delivery

✍ Scribed by Marieke A. E. M. van der Aa; Enrico Mastrobattista; Ronald S. Oosting; Wim E. Hennink; Gerben A. Koning; Daan J. A. Crommelin

Book ID: 106492753
Publisher: Springer US
Year: 2006
Tongue: English
Weight: 463 KB
Volume: 23
Category: Article
ISSN: 0724-8741
DOI: 10.1007/s11095-005-9445-4

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## Abstract ## Background Neuron‐specific, nonviral gene delivery vehicles are useful tools for the potential treatment of neurological disease and spinal cord injury. For minimally invasive, peripheral administration, gene carriers must efficiently mediate uptake at axon terminals, retrograde axo