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The nuclear overhauser effect and structural factors determining the conformations of disaccharide glycosides

✍ Scribed by Grigory M. Lipkind; Alexander S. Shashkov; Suren S. Mamyan; Nikolay K. Kochetkov

Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
786 KB
Volume
181
Category
Article
ISSN
0008-6215

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✦ Synopsis

Conformations

of (l-2)-, (l&+3)-, and (l-4)linked disaccharide methyl glycosides involving aldohexopyranose residues have been studied on the basis of the inter-unit n.0.e. and theoretical calculations using atom-atom potential functions. The preferred conformations and the n.0.e. values are determined by the absolute configurations of constituent residues, the configuration and position of the glycosidic linkage, and the orientation of the protons at the aglycon carbon associated with the glycosidic linkage and the adjacent carbons.

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