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The Nuclear Import of the Small GTPase Rac1 is Mediated by the Direct Interaction with Karyopherin α2

✍ Scribed by Kirstin Sandrock; Heike Bielek; Kristina Schradi; Gudula Schmidt; Norbert Klugbauer


Book ID
111268473
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
929 KB
Volume
11
Category
Article
ISSN
1398-9219

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The interaction of the low-molecular-weight GTP-binding protein rap2 with the cytoskeleton from thrombin-aggregated platelets was investigated by inducing depolymerization of the actin filaments, followed by in vitro-promoted repolymerization. We found that the association of rap2 with the cytoskele