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The NR1 subunit of NMDA receptor regulates monocyte transmigration through the brain endothelial cell barrier

✍ Scribed by Arie Reijerkerk; Gijs Kooij; Susanne M. A. Van Der Pol; Thomas Leyen; Kim Lakeman; Bert Van Het Hof; Denis Vivien; Helga E. De Vries

Book ID
111183873
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
442 KB
Volume
113
Category
Article
ISSN
0022-3042

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## Abstract We have investigated the effects of __Chlamydia pneumoniae__ on human brain endothelial cells (HBMECs) and human monocytes as a mechanism for breaching the blood‐brain barrier (BBB) in Alzheimer's disease (AD). HBMECs and peripheral blood monocytes may be key components in controlling t