The NPY system in stress, anxiety and depression
โ Scribed by Markus Heilig
- Book ID
- 113824250
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 451 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0143-4179
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The acute response to stress is embodied in the `ยฎght or ยฏight reaction', inducing a state of anxiety. When stress is longcontinued, depression may develop insidiously under the cloak of continuing anxiety symptoms. Depression inhibits the ability to cope with stress and so a `vicious circle' become
Neuropeptide Y (NPY) has neuromodulatory actions on multiple brain functions including endocrine, behavioral, and circadian processes and has been implicated in the pathophysiology of both anxiety and depression. Behavioral studies suggest that NPY is a potent anxiolytic, whereas CRF is anxiogenic,