The novel immunosuppressive enzyme IL4I1 is expressed by neoplastic cells of several B-cell lymphomas and by tumor-associated macrophages

Differentiation of EL4 lymphoma cells by

Differentiation of EL4 lymphoma cells by tumoral environment is associated with inappropriate expression of the large chondroitin sulfate proteoglycan PG-M and the tumor-associated antigen HTgp-175

✍ Pieter Rottiers; Tine Verfaillie; Roland Contreras; Hilde Revets; Marjory Desmed 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 135 KB

## Progression to malignancy of transformed cells involves complex genetic alterations and aberrant gene expression patterns. While aberrant gene expression is often caused by alterations in individual genes , the contribution of the tumoral environment to the triggering of this gene expression is