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The novel HSP90 inhibitor STA-9090 exhibits activity against Kit-dependent and -independent malignant mast cell tumors

โœ Scribed by Tzu-Yin Lin; Misty Bear; Zhenjian Du; Kevin P. Foley; Weiwen Ying; James Barsoum; Cheryl London

Book ID
113616491
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
997 KB
Volume
36
Category
Article
ISSN
0301-472X

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## Abstract Osteosarcoma (OSA), the most common malignant bone tumor in dogs and children, exhibits a similar clinical presentation and molecular biology in both species. Unfortunately, 30โ€“40% of children and 90% of dogs still die of disease despite aggressive therapy. The purpose of this study was