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The Notch-Hes pathway in mammalian neural development

✍ Scribed by KAGEYAMA, Ryoichiro; OHTSUKA, Toshiyuki

Book ID
110020382
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
339 KB
Volume
9
Category
Article
ISSN
0007-0610

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## Abstract Notch signaling dictates cell fate and critically influences cell proliferation, differentiation, and apoptosis in metazoans. Multiple factors at each stepβ€”ligands, receptors, signal transducers and effectorsβ€”play critical roles in executing the pleiotropic effects of Notch signaling. L