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The Norwegian founder mutations in BRCA1: high penetrance confirmed in an incident cancer series and differences observed in the risk of ovarian cancer

✍ Scribed by K Heimdal; L Mæhle; J Apold; J.C Pedersen; P Møller


Book ID
117660173
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
218 KB
Volume
39
Category
Article
ISSN
0959-8049

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Previous mutational analysis for BRCA gene mutations in sporadic ovarian cancer occurring in Chinese patients in Hong Kong identified six germline BRCA1 mutations and one germline BRCA2 mutation, six of which were novel (Khoo et al., 2000). Knowledge of BRCA gene mutations in the Chinese population