๐”– Bobbio Scriptorium
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The normal membrane resting potential of mammalian skeletal muscle measured in vivo

โœ Scribed by Bennett, A. L. ;Ware, F. ;Dunn, A. L. ;McIntyre, A. R.

Publisher
Wiley (John Wiley & Sons)
Year
1953
Tongue
English
Weight
772 KB
Volume
42
Category
Article
ISSN
0095-9898

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โœฆ Synopsis

The technique for direct measurement of the difference in potential between the inside and outside of single muscle cells was provided by Graham and Gerard ('46) when they first penetrated frog muscle cells with micro-electrodes consistiiig of extremely fine glass capillaries containing saline. Ling and Gerard ('49) described the preparation and use of such electrodes with a tip-diameter of less than 1 p and presented preliminary experiments in which the electrodes were filled with 3 molar instead of isotonic KCl. These authors and also Nastuk and Hodgkin ('50) have reported detailed studies on the resting and action potentials of frog muscle fibers. The same technique has been used by Nastuk

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