๐”– Bobbio Scriptorium
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The normal membrane potential of frog sartorius fibers

โœ Scribed by Ling, G. ;Gerard, R. W.

Publisher
Wiley (John Wiley & Sons)
Year
1949
Tongue
English
Weight
627 KB
Volume
34
Category
Article
ISSN
0095-9898

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โœฆ Synopsis

An earlier paper (Graliaiii aiid Gerard, '47) discussed the adrantages of stud?-iiig cell membrane potentials in singlyimpaled muscle fibers of the frog sartorius and described a method for doing so. A capillary electrode, of tip diameter 2-5 p, was used in these experiments aiid insertion into a fiber caused obvions damage. Measured tlius, potential d u e s varied from fiber to fiber, oTTer 40 to 80 iiiV, so that for niariy types of study only an extensive statistical approach would h a r e been possible. Since the smaller capillaries were clearly more satisfactory, we have pushed in the diyection of drawing and filling microelectrodes of well under 1 p tip-diameter and properly tapered and were rewarded by obtaining highly coiistaiit membrane potentials. METHOD

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