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The nonlinear kinetics of desipramine and 2-hydroxydesipramine in plasma

✍ Scribed by Cooke, Robert G; Warsh, Jerry J; Stancer, Harvey C; Reed, Kenton L; Persad, Emmanuel


Book ID
109843433
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
483 KB
Volume
36
Category
Article
ISSN
0009-9236

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The protein binding characteristics of prednisone and prednisolone were determined in human and rabbit plasma and in a 4.7 per cent human serum albumin (HSA) solution. The influence of plednisolone on prednisone binding in human plasma was also examined. Prednisolone exhibited nonlinear binding and