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The non-involvement of cysteine or cystine in the membrane receptor site of insulin

โœ Scribed by Christensen, Virginia ;Maturo, Joseph M.


Book ID
105242025
Publisher
Springer-Verlag
Year
1972
Weight
359 KB
Volume
9
Category
Article
ISSN
0001-5563

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High-affinity binding of insulin to receptors in human erythrocyte membranes occurred at the external surface, but not at the cytoplasmic surface of the plasma membrane, as assessed by insulin binding to right-side-out and inside-out membrane vesicles. Even after prolonged (3 h) incubation at 22"C,