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The nociceptin/orphanin FQ-NOP receptor antagonist effects on an animal model of sepsis

✍ Scribed by Dickson Carvalho; Fabricia Petronilho; Francieli Vuolo; Roberta Albino Machado; Larissa Constantino; Remo Guerrini; Girolamo Calo; Elaine Cristina Gavioli; Emílio Luiz Streck; Felipe Dal-Pizzol


Publisher
Springer
Year
2008
Tongue
English
Weight
285 KB
Volume
34
Category
Article
ISSN
1432-1238

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The nociceptin/orphanin FQ (NOP) recepto
✍ Naomi P. Visanji; Rob M.A. de Bie; Tom H. Johnston; Andrew C. McCreary; Jonathan 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 540 KB

## Abstract The anti‐parkinsonian and levodopa‐sparing potential of the nociceptin/orphanin FQ receptor (NOP) antagonist J‐113397 has been demonstrated in rodent models of Parkinson's disease. Here, we describe the levodopa‐sparing potential of J‐113397 in MPTP‐lesioned marmosets. Coadministration