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The NMR structure of the TC10- and Cdc42-interacting domain of CIP4

✍ Scribed by Yoshihiro Kobashigawa; Hiroyuki Kumeta; Daisuke Kanoh; Fuyuhiko Inagaki

Publisher
Springer Netherlands
Year
2009
Tongue
English
Weight
798 KB
Volume
44
Category
Article
ISSN
0925-2738

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## Abstract Tensin is a protein confined at those discrete and specialized regions of the plasma membrane, known as focal adhesions. It contains, at the C‐terminus, a phosphotyrosine binding (PTB) domain that can interact with the cytoplasmic tail of β‐integrins and is necessary for localization of