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The NMDA antagonist MK-801 induces hyperalgesia and increases CSF excitatory amino acids in rats: Reversal by guanosine

✍ Scribed by André P. Schmidt; Adriano B.L. Tort; Patrícia P. Silveira; Ana Elisa Böhmer; Gisele Hansel; Luisa Knorr; Cristhine Schallenberger; Carla Dalmaz; Elaine Elisabetsky; Rosa H. Crestana; Diogo R. Lara; Diogo O. Souza

Book ID
113841633
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
319 KB
Volume
91
Category
Article
ISSN
0091-3057

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Non-NMDA excitatory amino acid receptors in the ventral tegmental area mediate systemic dizocilpine (MK-801) induced hyperlocomotion and dopamine release in the nucleus accumbens
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This study investigated the putative role of non-NMDA excitatory amino acid (EAA) receptors in the ventral tegmental area (VTA) for the increase in dopamine (DA) release in the nucleus accumbens (NAC) and behavioral stimulation induced by systemically administered dizocilpine (MK-801). Microdialysis