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The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

โœ Scribed by Maria Carlsson; A. Carlsson

Book ID
105137539
Publisher
Springer
Year
1989
Tongue
English
Weight
452 KB
Volume
75
Category
Article
ISSN
1435-1463

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Effects of an NMDA-receptor antagonist,
Effects of an NMDA-receptor antagonist, MK-801, on central locomotor programming in the rabbit
โœ F. Fenaux; M. Corio; R. Palisses; D. Viala ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 962 KB

NMDA has been shown to disclose spinal fictive locomotor activity in various in vitro preparations. In the present work the NMDA-mediated effects of endogenously released excitatory aminoacids (EAA) on fictive locomotion in the adult rabbit preparation were assessed in vivo using systemic injections