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The Nitric Oxide-Endothelin-1 Connection

✍ Scribed by David Alonso; Marek W. Radomski

Book ID
110415662
Publisher
Springer
Year
2003
Tongue
English
Weight
405 KB
Volume
8
Category
Article
ISSN
1382-4147

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## Abstract The complex pathogenesis of chronic renal disease (CRD) depends on endothelin (ET) axis (ETs and ET receptors) and nitric oxide (NO) because of their vasoactive effects and their role in general modulation of vascular homeostasis. Various renal cells synthesize ETs and NO that play a si