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The nicotine metabolite, cotinine, attenuates glutamate (NMDA) antagonist-related effects on the performance of the five choice serial reaction time task (5C-SRTT) in rats

✍ Scribed by Alvin V. Terry Jr; Jerry J. Buccafusco; R. Foster Schade; Leah Vandenhuerk; Patrick M. Callahan; Wayne D. Beck; Elizabeth J. Hutchings; James M. Chapman; Pei Li; Michael G. Bartlett


Book ID
113489725
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
740 KB
Volume
83
Category
Article
ISSN
0006-2952

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✍ Maria Mazurkiewicz; Jouni SirviΓΆ; Paavo Riekkinen Sr. πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 English βš– 793 KB

The present study investigated whether pharmacological stimulation of the GABAergic system can affect attention. The effects of vigabatrin, a novel antiepileptic drug, on the performance of rats in a 5-choice serial reaction time task assessing selective attention were studied. The effects of acute