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The NG2 chondoitin sulfate proteoglycan: role in malignant progression of human brain tumours

✍ Scribed by M. Chekenya; H.K. Rooprai; D. Davies; J.M. Levine; A.M. Butt; G.J. Pilkington


Book ID
117563920
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
219 KB
Volume
17
Category
Article
ISSN
0736-5748

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Neuroglycan C (NGC) is a transmembrane chondroitin sulfate proteoglycan with an EGF module. We studied the expression of NGC in the human brain, mainly in the hippocampus, and confirmed some observations by conducting experiments using rat brain. In humans, NGC mRNA was expressed exclusively in the