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The newly established human liver cell line: a potential cell source for the bioartificial liver in the future

✍ Scribed by Liu, Hongling; You, Shaoli; Rong, Yihui; Wu, Yichen; Zhu, Bing; Wan, Zhihong; Liu, Wanshu; Mao, Panyong; Xin, Shaojie

Book ID
120502277
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
457 KB
Volume
26
Category
Article
ISSN
0914-7470

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## Abstract Extrahepatic bioartificial liver devices should provide an intact urea cycle to detoxify ammonia. The C3A cell line, a subclone of the hepatoma‐derived HepG2 cell line, is currently used in this context as it produces urea, and this has been assumed to be reflective of ammonia detoxific