## Abstract Cell based smallpox vaccines are to be welcomed, but any decision to vaccinate whole populations must await firstly better intelligence about the gravity of the threat from bioterrorists, including their ability to release smallpox in such a way that wide dissemination could take place;
The new cell culture smallpox vaccine should be offered to the general population
✍ Scribed by William Bicknell; Kenneth James
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 117 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1052-9276
- DOI
- 10.1002/rmv.382
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
A series of major factors must be weighed in deciding whether or not, and to what extent, a particular country should consider pre‐exposure vaccination for smallpox. These include the risk of a bioterrorist attack using smallpox, the risk of secondary spread from another country, the risks and benefits of vaccination, the effectivenes s of vaccination pre‐ and post‐exposure, the prevalence of immunocompromised persons, the capacity of the medical care delivery system and the wealth of a nation. We review here the issues and variables relevant for policy making, propose a framework for country‐specific decision making and suggest the World Health Organization has a key role to play, particularly with regard to lower‐income countries. In doing so, we support the proposition. Copyright © 2003 John Wiley & Sons, Ltd.
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