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The neurotrophic effects of PACAP in PC12 cells: control by multiple transduction pathways

✍ Scribed by Aurélia Ravni; Steve Bourgault; Alexis Lebon; Philippe Chan; Ludovic Galas; Alain Fournier; Hubert Vaudry; Bruno Gonzalez; Lee E. Eiden; David Vaudry

Book ID
111179577
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
205 KB
Volume
98
Category
Article
ISSN
0022-3042

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## Abstract We studied whether nerve growth factor (NGF) can affect the membrane potential and conductance of PC12 cells. We demonstrate that NGF depolarizes the membrane of PC12 cells within a minute and by using transfected NIH 3T3‐Trk and ‐p75 cells we show that both the high affinity NGF recept