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The neuroprotective effect of NGF against glutamate neurotoxicity is mediated by P75 neurotrophin receptor in cortical cultures

✍ Scribed by Toshiaki Kume; Hiroyuki Nishikawa; Hiroko Tomioka; Shuji Kaneko; Akinori Akaike

Book ID: 117365140
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 112 KB
Volume: 31
Category: Article
ISSN: 0168-0102
DOI: 10.1016/s0168-0102(98)82415-2

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re