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The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways

โœ Scribed by Qiu-Hua Guan; Dong-Sheng Pei; Quan-Guang Zhang; Zhi-Bin Hao; Tian-Le Xu; Guang-Yi Zhang


Book ID
113500289
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
487 KB
Volume
1035
Category
Article
ISSN
0006-8993

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โœ Dong-Sheng Pei; Qiu-Hua Guan; Ya-Feng Sun; Qing-Xiu Zhang; Tian-Le Xu; Guang-Yi ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 370 KB

## Abstract To investigate whether the kainate (KA) receptors subunit GluR6 is involved in the neuronal cell death induced by cerebral ischemia followed by reperfusion, the antisense oligodeoxynucleotides (ODNs) of GluR6 were used to suppress the expression of GluR6 by intracerebroventricular infus