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The neurohumoral and hemodynamic effects of acute vasopeptidase inhibition in experimental hypertension

✍ Scribed by Maniu, Celin V.; Meyer, Donna M.; Redfield, Margaret M.

Book ID
122146224
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
126 KB
Volume
39
Category
Article
ISSN
1558-3597

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The hemodynamic and neurohumoral effects of a single oral dose (0.4 mg) of the novel centrally acting antihypertensive agent moxonidine were investigated over 4 hours in ten patients with essential hypertension (WHO I-II). Pulmonary pressure indices and cardiac output were determined both at rest an