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The neuroendocrinological profile of roxindole, a dopamine autoreceptor agonist, in schizophrenic patients

✍ Scribed by G. Gründer; H. Wetzel; A. Hillert; E. Jochum; C. Hiemke; O. Benkert

Publisher
Springer
Year
1995
Tongue
English
Weight
797 KB
Volume
117
Category
Article
ISSN
0033-3158

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## Abstract We have examined the hypothesis that a variable number of tandem repeats in the third cytoplasmic loop of the dopamine D4 receptor influences clinical response to clozapine using a sample of 189 schizophrenic patients. Alleles of the 48‐bp repeat, which range from two to ten copies in t