Two Signal Activation as an Explanation
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Jonathan Swinton; A.Nicola Schweitzer; Roy M. Anderson
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Article
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1994
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Elsevier Science
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English
โ 380 KB
Much work on the induction of non-responsiveness in lymphocytes suggests that it takes two signals to activate a cell correctly, and that receipt of the first signal alone not only causes suboptimal response, but also subsequent non-responsiveness or anergy. This paper discusses not anergy, but the