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The nascent polypeptide-associated complex (NAC) of yeast functions in the targeting process of ribosomes to the ER membrane

✍ Scribed by Brigitte Wiedmann; Siegfried Prehn


Book ID
117111374
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
247 KB
Volume
458
Category
Article
ISSN
0014-5793

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The three subunits of the nascent polypeptide-associated complex ( , 1 , 3 ) in Saccharomyces cerevisiae are encoded by three genes (EGD2, EGD1, BTT1). We found the complex bound to ribosomes via the -subunits in a salt-sensitive manner, in close proximity to nascent polypeptides. Estimation of the