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The NADPH Oxidase Components p47phox and p40phox Bind to Moesin through Their PX Domain

✍ Scribed by Frans B. Wientjes; Emer P. Reeves; Vukic Soskic; Heinz Furthmayr; Anthony W. Segal

Book ID
115589029
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
148 KB
Volume
289
Category
Article
ISSN
0006-291X

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## Abstract Activation of phagocytic NADPH oxidase requires association of its cytosolic subunits with the membrane‐bound flavocytochrome. Extensive phosphorylation of the p47^__phox__^ subunit of NADPH oxidase marks the initiation of this activation process. The p47^__phox__^ subunit then transloc