The NADH Electrochemical Detection Performed at Carbon Nanofibers Modified Glassy Carbon Electrode

✍ Scribed by Adina Arvinte; Federica Valentini; Antonio Radoi; Fabiana Arduini; E. Tamburri; Lucian Rotariu; Giuseppe Palleschi; Camelia Bala

• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 205 KB
• Volume: 19
• Category: Article
• ISSN: 1040-0397
• DOI: 10.1002/elan.200703879

✦ Synopsis

Abstract

In this work, the capability of carbon nanofibers to be used for the design of catalytic electrochemical biosensors is demonstrated. The direct electrochemistry of NADH was studied at a glassy carbon electrode modified using carbon nanofibers. A decrease of the oxidation potential of NADH by more than 300 mV is observed in the case of the assembled carbon nanofiber‐glassy carbon electrode comparing with a bare glassy carbon electrode. The carbon nanofiber‐modified electrode exhibited a wide linear response range of 3×10^−5^ to 2.1×10^−3^ mol L^−1^ with a correlation coefficient of 0.997 for the detection of NADH, a high specific sensitivity of 3637.65 (μA/M cm^2^), a low detection of limit (LOD=3__σ__) of 11 μM, and a fast response time (3 s). These results have confirmed the fact that the carbon nanofibers represent a promising material to assemble electrochemical sensors and biosensors.