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The N4 nitrogen of pirenzepine is responsible for selective binding of the M1 subtype human muscarinic receptor

✍ Scribed by Nicholas J. Murgolo; Joseph Kozlowski; Melissa A.B. Tice; Frank P. Hollinger; Joan E. Brown; Guowei Zhou; Lisa A. Taylor; Robert D. McQuade


Book ID
108038996
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
234 KB
Volume
6
Category
Article
ISSN
0960-894X

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The relative selectivity of anticholiner
✍ Dr. Robert E. Burke πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 775 KB

Anticholinergic drugs are used to treat a number of neurologic disorders, inctuding parkinsonism, vestibular disturbances, and dystonia. Traditionally, these drugs have been thought to act in similar fashion, as competitive antagonists at a single class of muscarink receptors, and not to differ sign