The N-terminal domain of Plasmodium falciparum circumsporozoite protein represents a target of protective immunity
β Scribed by Silayuv E. Bongfen; Patricia M. Ntsama; Sandra Offner; Thomas Smith; Ingrid Felger; Marcel Tanner; Pedro Alonso; Issa Nebie; Jackeline F. Romero; Olivier Silvie; Ralph Torgler; Giampietro Corradin
- Book ID
- 116961009
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 532 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0264-410X
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π SIMILAR VOLUMES
A polypeptide of 69 amino acids (PbCS 242-310) encompassing the C-terminal region of the circumsporozoite protein of Plasmodium berghei (PbCS) was generated using solid-phase peptide synthesis. The immunological and protective properties of peptide PbCS 242-310 were studied in BALB/c mice (H-2d). Tw
## Abstract Merozoite surface protein 2 (MSP2) is a GPIβanchored protein on the surface of the merozoite stage of the malaria parasite Plasmodium falciparum. It is largely disordered in solution, but has a propensity to form amyloidβlike fibrils under physiological conditions. The Nβterminal conser