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The N-terminal domain of APJ, a CNS-based coreceptor for HIV-1, is essential for its receptor function and coreceptor activity

✍ Scribed by Naiming Zhou; Xiaoling Zhang; Xuejun Fan; Elias Argyris; Jianhua Fang; Edward Acheampong; Garrett C DuBois; Roger J Pomerantz

Book ID
113945700
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
337 KB
Volume
317
Category
Article
ISSN
0042-6822

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The N-terminal domain of GPR61, an orphan G-protein-coupled receptor, is essential for its constitutive activity
✍ Masaru Toyooka; Takashi Tujii; Shigeki Takeda 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB

## Abstract G‐protein‐coupled receptor 61 (GPR61) is an orphan receptor that is abundantly expressed in the brain, which suggests its involvement in various physiological functions in the central nervous system. It couples with Gs and shows constitutive activity. To investigate the role of the N‐te