The N-terminal arms of λ repressor wrap around the operator DNA
✍ Scribed by Pabo, Carl O.; Krovatin, William; Jeffrey, Andrea; Sauer, Robert T.
- Book ID
- 109727095
- Publisher
- Nature Publishing Group
- Year
- 1982
- Tongue
- English
- Weight
- 419 KB
- Volume
- 298
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/298441a0
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We have carried out molecular dynamics simulation of the N-terminal domain of the repressor protein in a surrounding environment including explicit waters and ions. We observe two apparent dynamics substates in the nanosecond protein simulation, the transition occurring around 500 ps. The existence
The 197 amino acid c repressor of the temperate Rhizobium meliloti phage 16-3 still regulates the OR operator of the phage after removal of its carboxyl terminal region. When cloned in the low-copy-number plasmid pGA46, a severely truncated variant (R1-77), which retains only the first 77 amino acid