✦ LIBER ✦

The Mystery of Mismatch Repair Deficiency: Lynch or Lynch-like?

✍ Scribed by Boland, C. Richard

Book ID: 120448254
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 224 KB
Volume: 144
Category: Article
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2013.03.014

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The mechanism of mismatch repair and the

The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome

✍ MartÃn-LÃ³pez, Juana V.; Fishel, Richard 📂 Article 📅 2013 🏛 Springer Netherlands 🌐 English ⚖ 474 KB

Somatic Mutations in MLH1 and MSH2 Are a

Somatic Mutations in MLH1 and MSH2 Are a Frequent Cause of Mismatch-Repair Deficiency in Lynch Syndrome-Like Tumors

✍ Mensenkamp, Arjen R.; Vogelaar, Ingrid P.; van Zelst–Stams, Wendy A.G.; Goossens 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 297 KB

DNA Alterations in Lynch Syndrome || The

DNA Alterations in Lynch Syndrome || The Role of Epimutations of the Mismatch Repair Genes in the Development of Lynch Syndrome Related Cancers

✍ Vogelsang, Matjaž 📂 Article 📅 2013 🏛 Springer Netherlands ⚖ 793 KB

Identification of Lynch syndrome mutatio

Identification of Lynch syndrome mutations in the MLH1–PMS2 interface that disturb dimerization and mismatch repair

✍ Jan Kosinski; Inga Hinrichsen; Janusz M. Bujnicki; Peter Friedhoff; Guido Plotz 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 423 KB 👁 2 views

Missense alterations of the mismatch repair gene MLH1 have been identified in a significant proportion of individuals suspected of having Lynch syndrome, a hereditary syndrome that predisposes for cancer of colon and endometrium. The pathogenicity of many of these alterations, however, is unclear. A

T1723 Variable Immunohistochemical Stain

T1723 Variable Immunohistochemical Staining Patterns of the Mismatch Repair Proteins: A Potential Pitfall in Screening for Lynch Syndrome

✍ Radu, Oana M.; Nikiforova, Marina; Farkas, Linda M.; Krasinskas, Alyssa M. 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 45 KB

Improving Lynch Syndrome Diagnostics by

Improving Lynch Syndrome Diagnostics by Multiplex Snapshot Assays for the Detection of Mismatch Repair Gene LOH in MSI-H Tumors

✍ Celine H. Leenen; Ina R. Geurts-Giele; Erik Jan Dubbink; Ernst J. Kuipers; Moniq 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 294 KB