## Abstract Galactocerebroside (GalC) and sulfatide are abundant myelin lipids. In mice incapable of synthesizing these lipids, myelin is thin and regionally unstable and exhibits several subtle structural abnormalities. Although galactolipid‐null mice have been beneficial in the analysis of galact
The myelinated axon is dependent on the myelinating cell for support and maintenance: Molecules involved
✍ Scribed by J.M. Edgar; J. Garbern
- Book ID
- 102381447
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 208 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0360-4012
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The myelin‐forming cells, oligodendrocytes and Schwann cells, extend processes that spirally wrap axons and provide the insulation that allows rapid saltatory conduction. Recent data suggest a further role for the myelin‐forming cells in axonal support and maintenance. This Mini‐Review summarises some of the data that support this view and highlights the molecules involved. © 2004 Wiley‐Liss, Inc.
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