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The Mycoplasma arthritidis T-cell mitogen MAM: a model superantigen

โœ Scribed by Barry C Cole; Curtis L Atkin


Book ID
103583665
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
930 KB
Volume
12
Category
Article
ISSN
0167-5699

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Mycoplasma arthritidis produces an as yet undefined soluble molecule (MAS) that has a potent mitogenic effect on T cells of several species. We have used cloned human cytotoxic and proliferative T lymphocytes to dissect the molecular mechanism of T cell activation by this mitogen. Reactivity to MAS