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The Muscarinic Receptor Adenylate Cyclase Complex of Rat Striatum: Desensitization Following Chronic Inhibition of Acetylcholinesterase Activity

✍ Scribed by Maria C. Olianas; Pierluigi Onali; Joan P. Schwartz; N. H. Neff; E. Costa


Book ID
111172814
Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
443 KB
Volume
42
Category
Article
ISSN
0022-3042

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We studied the effects of acute and chronic in vivo inhibition of acetylcholinesterase on both the density and function of brain muscarinic cholinergic receptors. Adult male rats were treated either once or multiple times over a period of 10 days with the irreversible acetylcholinesterase inhibitor