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The murine homolog of TB2/DP1, a gene of the familial adenomatous polyposis (FAP) locus

✍ Scribed by Eva E. Prieschl; Gunther G. Pendl; Nathalie E. Harrer; Thomas Baumruker


Book ID
116133368
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
327 KB
Volume
169
Category
Article
ISSN
0378-1119

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Mutation analysis of the adenomatous pol
✍ Marie Luise Bisgaard; RASMUS S. Ripa; Steffen BΓΌlow πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 26 KB πŸ‘ 2 views

## Development of one hundred or more adenomas in the colon and rectum is diagnostic for the dominantly inherited, autosomal disease Familial Adenomatous Polyposis (FAP). It is possible to identify a mutation in the Adenomatous Polyposis Coli (APC) gene in approximately 80% of the patients, and alm

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✍ Clara Ruiz-Ponte; Ana Vega; Angel Carracedo; Francisco Barros πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 26 KB πŸ‘ 2 views

Germline mutations in the tumor-suppresor APC gene are associated with hereditary familial adenomatous polyposis (FAP) and somatic mutations are common in sporadic colorectal cancer. In this study, we report the identification of three novel germline mutations: 1682-1683insA, 3252-3253insAT, 3544A>T

Cranial desmoid tumor associated with ho
✍ Deepthi C. de Silva; Morag F. Wright; David A. J. Stevenson; Caroline Clark; Eli πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 502 KB

## BACKGROUND. Familial adenomatous polyposis (FAP) is a dominantly inherited disorder characterized by the presence of more than 100 adenomatous polyps in the colon and rectum starting in the second decade of life. FAP is associated with extra colonic manifestations, including desmoid tumors.