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The multiple functions of collagen XVIII in development and disease

✍ Scribed by Lotta Seppinen; Taina Pihlajaniemi

Book ID
116729954
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
519 KB
Volume
30
Category
Article
ISSN
0945-053X

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## Abstract Knobloch syndrome is characterized by a congenital generalized eye disease and cranial defect. Pathogenic mutations preferentially lead to a deletion or functional alteration of collagen XVIII's most C‐terminal endostatin domain. Endostatin can be released from collagen XVIII and is a p