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The multiple endocrine neoplasia type 2 syndromes and Hirschsprung disease are due to different mutations in the receptor tyrosine kinase ret

✍ Scribed by Bruce Ponder; Lois Mulligan; Charis Eng; Patrick Edery; Stanislas Lyonnet; Darrin Smith; Alan Tunnacliffe; John Kwok


Book ID
119106256
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
102 KB
Volume
77
Category
Article
ISSN
0165-4608

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Mutations of the RET proto-oncogene in t
✍ Charis Eng; Lois M. Mulligan πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 225 KB πŸ‘ 2 views

## Communicated by Martin Bobrow The RET proto-oncogene codes for a receptor tyrosine kinase thought to play a role in the development of neural crest and its derivatives. Mutations in the RET proto-oncogene have been found in patients with the multiple endocrine neoplasia type 2 syndromes (MEN 2)