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The multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasis

✍ Scribed by Najla Arshad; Sandhya S. Visweswariah


Book ID
118442915
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
349 KB
Volume
586
Category
Article
ISSN
0014-5793

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## Abstract Guanylyl cyclase C (GC‐C), a transmembrane receptor for bacterial heat‐stable enterotoxin and the mammalian peptides guanylin and uroguanylin, mediates intestinal ion secretion and affects intestinal cell growth via cyclic GMP signaling. In intestinal tumors, GC‐C expression is maintain