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The Multifunctional Role of mTOR in Innate Immunity: Implications for Transplant Immunity

✍ Scribed by M. D. Säemann; M. Haidinger; M. Hecking; W. H. Hörl; T. Weichhart

Book ID
114805320
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
106 KB
Volume
9
Category
Article
ISSN
1600-6135

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## Abstract The mammalian target of rapamycin inhibitors (mTOR‐Is) sirolimus and everolimus represent a class of proliferation signal inhibitors with a wide spectrum of activities, including suppression of T‐cell proliferation and reduction of tumor growth. In solid‐organ transplantation, mTOR inhi