Deciphering interactions of the aminogly
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Lingzhi Wu; Engin H. Serpersu
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Article
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2009
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Wiley (John Wiley & Sons)
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English
β 211 KB
## Abstract Aminoglycoside phosphotransferase(3β²)βIIIa (APH) is the enzyme with broadest substrate range among the phosphotransferases that cause resistance to aminoglycoside antibiotics. In this study, the thermodynamic characterization of interactions of APH with its ligands are done by determini