Analysis of polyglutamine-coding repeats
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Rubinsztein, David C.; Leggo, Jayne; Crow, Timothy J.; DeLisi, Lynn E.; Walsh, C
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Article
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1996
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John Wiley and Sons
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English
โ 411 KB
๐ 2 views
## ~ A new class of disease (including Hunting ton disease, Kennedy disease, and spinocerebellar ataxias types 1 and 3) results from abnormal expansions of CAG trinucleotides in the coding regions of genes. In all of these diseases the CAG repeats are thought to be translated into polyglutamine tr