The Multi PDZ Domain Protein MUPP1 as a Putative Scaffolding Protein for Organizing Signaling Complexes in the Acrosome of Mammalian Spermatozoa

The Multi-PDZ domain protein MUPP1 as a

The Multi-PDZ domain protein MUPP1 as a lipid raft-associated scaffolding protein controlling the acrosome reaction in mammalian spermatozoa

✍ Frauke Ackermann; Nele Zitranski; Diana Heydecke; Beate Wilhelm; Thomas Guderman 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 551 KB

## Abstract The success of acrosomal exocytosis, a complex process with a variety of interrelated steps, relies on the coordinated interaction of participating signaling molecules. Since scaffolding proteins are known to spatially organize sequential signaling pathways, we examined whether the Mult