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The Mucosal Immune Response in a Mouse Model of Amebic Colitis

✍ Scribed by Eric Houpt; Richard Vines; Victoria Camerini; Lauren Lockhart; William Petri Jr.

Book ID
114179738
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
24 KB
Volume
31
Category
Article
ISSN
0188-4409

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## Background: The G protein alpha subunit type-2 (G␣ i 2)-deficient mouse develops inflammatory bowel disease (IBD) with increased severity in mice on a 129SvEv (129) background compared to the C57BL/6 (B6) background. Since dendritic cells (DCs) are key cells of innate immunity, we determined wh